Oxidants, antioxidants and the ischemic brain
نویسندگان
چکیده
منابع مشابه
Oxidants, antioxidants and the ischemic brain.
Despite numerous defenses, the brain is vulnerable to oxidative stress resulting from ischemia/reperfusion. Excitotoxic stimulation of superoxide and nitric oxide production leads to formation of highly reactive products, including peroxynitrite and hydroxyl radical, which are capable of damaging lipids, proteins and DNA. Use of transgenic mutants and selective pharmacological antioxidants has ...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2004
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.01022